Clenbuterol is quite anti-catabolic and/or anabolic in almost every (animal) study ever done on it, although this hasn’t been studied or confirmed in human studies . Also, a trend we see with Clenbuterol administration in animals is that the doses used are very high- more than anyone I’ve ever heard of actually taking. So, what I’m saying is that if Clenbuterol is anabolic or anti-catabolic in humans, only mild anabolic or anti-catabolic effects can realistically be expected. We can take a look at horses given a human-like dose of clen (slightly over 1mcg/lb x2 a day) and exercised for nearly human-like times (20mins, 3x a week) showed very significant decreases in %fat (-17.6%) and fat mass (-19.5%). Interestingly, this significantly increased (+4.4%) at week 6 . This has been one of the reasons I have never believed in the 2 weeks on and 2 weeks theory of Clenbuterol administration. Why wouldn’t we want to use it for at least 6 weeks, considering the fact that it seems to have some profound effects during later administration. A “second wind” so to speak (get it? “second wind”? it’s an asthma med! Ha! Ok…moving along…). One of the primary drawbacks of Clenbuterol is that after a couple of weeks, it seems to stop working for most people. This is because it can cause a downregulation of pulmonary, cardiac and central nervous system beta-adrenergic receptors. This is why it seems to stop burning fat for most people at that point. To counteract this, you can take some Ketotifen, Benadryl, or Periactim every 3rd or 4th week that you remain on Clenbuterol. These are prescription anti-histimines, so they’ll make you drowsy (take before bedtime). Also, bear in mind that clen isn’t great for your heart, and can cause some issues there (enlargement of ventricles, etc…) but most studies showing Clen to cause heart problems are with animals, and even though the dosing is almost similar to what humans take (in some studies its within range of what would be double of a large human dose...). Again, it’s important to remember that animals have more beta-2 receptors and they cause certain event chains that humans’ beta-2 receptors may not, due to their relatively high concentrations. Clen causes cardiac hypertrophy to some degree, in some cases and even dose-dependent apoptotic and necrotic myocyte death . And since Clen depletes taurine as do most if not all beta-agonists, you may want to supplement your Clen use with some Taurine. (Red Bull?) One of the weirdest things about Clenbuterol is that even though it’s an asthma medication, studies have shown reduced exercise (cardiovascular) performance with Clen , but some also show that Clen can alleviate exercise induced asthma ! Clenbuterol is one of the easiest drugs to find proper dosing for, and I’ve always made the same recommendations as to finding the appropriate dose for you. Basically, start with 20mcgs upon rising. If the side effects (possible anxiety, and shaking or sweating) aren’t too pronounced, then repeat that same dose again later in the day, and then once again in that day (again, if you find you can tolerate the effects). If you start experiencing intolerable sides, then decrease the does to where it’s tolerable. If not, then start increasing the dose more, very gradually. Don’t go over 200mcgs, though…and keep your Blood Pressure at (or under) 140/90. If your Blood Pressure goes over that, reduce your dose. If side effects are intolerable, decrease your dose